Studies in non psoriatic murine animal model, fed with high fat diet, showed thepossibility of infliximab reverse steatosis triggered by poor diet.76 Another study in an animal model,with mice deficient in choline and with methionine-induced hepatitis, showed thatinfliximab (as anti-TNF-α drugs prototype) decreased fat infiltration andhepatic fibrosis.77 A case reportof a patient with rheumatoid arthritis using adalimumab demonstrated reduction ofsteatosis and improvement of liver function tests.78 This evidence concerns the gene TNF and rheumatoid arthritis.