TNF and psoriasis: Al-Mutairi et al. showed that the body weight reduction in obesepatients with psoriasis receiving immunobiological therapy can increase theeffectiveness of the drug, and Solomon et al. showed that theweight loss (greater than or equal to 5% of the initial weight) regardless ofthe type of diet is associated with a higher success rate in achieving controlof disease activity in patients with overweight or obesity with psoriaticarthritis treated with anti-TNF-α.31,32