Integrity and functions of sebaceous gland are essential for the development andactivity of hair follicles4stimulated by PPARγ.5 Micedepleted of the gene of this receptor lose the stem cells of the bulges and developfibrosing alopecia.5,6 PPARγ is indispensable forthe maintenance of stem cells of functional epithelium in hair follicles.5 Deletion of the PPARγ gene inthe bulge area of the hair resulted in a skin process is similar to LPPalopecia.6 The location ofthe inflammatory infiltrate is typically centered on the bulge region.21 Here, PPARG is linked to alopecia.