MKI67 and verrucous carcinoma: Besides, HPV infection was assumed to play a carcinogenic role in SCC arising in HS.[15] It was concluded that positive p16/HPV expression with high Ki67 was associated with basaloid/warty morphology of SCC, while negative p16/HPV expression with low Ki67 was associated with usual morphology.[16] However, our case (verrucous carcinoma) was inconsistent with the former conclusion since negative HPV/p16 expression with high Ki67 was demonstrated.