IL10 and glioblastoma: Sredni et al. reported that IL-10 is essential for tumour cell proliferation in a murine B16 melanoma cell line and two human primary cultures of stomach adenocarcinoma and glioblastoma (GBM), as its neutralization decreases the clonogenicity of malignant cells, whereas the addition of recombinant IL-10 increases cell proliferation [22].