BID and neoplasm: The results show that DMABTSPd(TSPd) led to the increase at Bid level (Supplementary Figure 6A and Figure 4F, **P < 0.01, vs DMSO-group), and the decrease at Bcl-2 level in a nude mouse tumor xenograft model (Supplementary Figure 6B and Figure 4F, **P < 0.01, vs DMSO-group).