Others found that double-strand DNA damage repair genes (including BARD1 and RAD51) were over-represented in the BM compared to matching BCs [63], and in a third example, gene expression (GEX) profiling of eight BM compared to unpaired but clinically matched BC found that overexpression of hexokinase 2 (HK2) was associated with poor survival [109]. Here, HK2 is linked to breast cancer.