NES and neoplasm: Our labeling with specific antibodies identified cells around and within vessels as CSCs or GSCs (nestin+/IQGAP1+), Tumor Associated Macrophages (TAMs) and endothelial cells (CD31+/IQGAP1+), microglia (Iba1+/CD31−/IQGAP1+) and, in addition to these well characterized kind of cells, colonies of IQGAP1+/Iba1+/nestin+ cells are found surrounding nestin+ cells (Figure 2K–O).