The observed IQGAP1+/Iba1+/nestin+ cells could represent a common ancestor for TAMs and GBM tumorigenic neural precursors and/or, probably, an interconvertible multipotent progenitor cell form of both kinds and/or glioblastoma amplifying cancer cells [33] (GSCs or progenitor cells). The gene discussed is IQGAP1; the disease is glioblastoma.