DNM1L and T-cell acute lymphoblastic leukemia: In addition to these gene modifications in Drp1-related pathways, co-culture with mesenchymal stem cells induces T-cell acute lymphoblastic leukemia cells to keep well-maintained mitochondrial dynamics, mitochondrial ROS levels, and chemoresistance via extracellular signal-regulated kinase activation-mediated phosphorylation of Drp1 at residue Ser-616 [66].