Among the most statistically enriched alternatively spliced genes in NDR vs RCM were those associated with cardiomyopathies (ANK2, CD36, DCN, DTNA, ITGAV, MYH7, SLC8A1, and TLR4), ventricular outflow obstruction (CD36, ENO3, MYH7, and PPP3CB), regulation of heart contraction (ANK2, CAMK2D, HRC, SLC8A1, and TPM3), actin cytoskeleton (CALD1, DST, PDLIM3, PEAK1, SEPT7, SVIL, and TPM3) and Z-disk (ANK2, DST, MYH7, OBSCN, PDLIM3, SLC8A1, and TTN) (ToppGene). This evidence concerns the gene ENO3 and cardiomyopathy.