Analysis of pathways that were dysregulated across cardiomyopathy phenotypes identified shared genes that were associated with extracellular matrix remodeling and thus likely fibrosis (THY1, CILP, OGN, THBS4, ASPN, HAPLN1,and SMOC2), as well as calcium (ADIPOQ, ASPN, THBS4, STAT4, and SMOC2). This evidence concerns the gene HAPLN1 and cardiomyopathy.