Analysis of pathways that were dysregulated across cardiomyopathy phenotypes identified shared genes that were associated with extracellular matrix remodeling and thus likely fibrosis (THY1, CILP, OGN, THBS4, ASPN, HAPLN1,and SMOC2), as well as calcium (ADIPOQ, ASPN, THBS4, STAT4, and SMOC2). The gene discussed is OGN; the disease is cardiomyopathy.