MYH6 and heart failure: These disease ontology terms include the following genes: plasminogen activator inhibitor-1 (SERPINE1) which has previously been shown to be involved in myocardial remodeling following ischemia reperfusion injury12, the well characterized cardiomyopathy associated α-myosin heavy chain 6 (MYH6)13, and several genes from the natriuretic peptide (NP) system which have well-known roles as biomarkers in heart failure (NPPA, NPPB, and NPPC)14.