Among the most statistically enriched alternatively spliced genes in NDR vs RCM were those associated with cardiomyopathies (ANK2, CD36, DCN, DTNA, ITGAV, MYH7, SLC8A1, and TLR4), ventricular outflow obstruction (CD36, ENO3, MYH7, and PPP3CB), regulation of heart contraction (ANK2, CAMK2D, HRC, SLC8A1, and TPM3), actin cytoskeleton (CALD1, DST, PDLIM3, PEAK1, SEPT7, SVIL, and TPM3) and Z-disk (ANK2, DST, MYH7, OBSCN, PDLIM3, SLC8A1, and TTN) (ToppGene). The gene discussed is PEAK1; the disease is cardiomyopathy.