On the basis of this in silico analysis, YAP1 and TEAD4 can both be recruited to TGFB2, TGM2, MYH9, MEF2C and ETS1. A recent report has shown that over 80% of YAP1/TAZ/TEAD-binding to DNA occurs at enhancers located over 10 kb from the transcriptional start site of target genes in MDA-MB-231 breast cancer cells23. The gene discussed is TGFB2; the disease is breast cancer.