They found EGFR gene deregulation in 25 out of 36 primary tumours and 29 out of 36 metastases, KRAS mutations in 16 out of 37 cancers and in 15 out of 37 metastases, and BRAF mutations in 2 out of 36 cancers and 2 out of 36 metastases. This evidence concerns the gene KRAS and neoplasm.