IGF1R and atherosclerosis: miR-138 promotes the proliferation and migration of VSMCs in db/db mice by suppressing the expression of SIRT1 [94], and miR-133a serves as a stimulatory factor for IGF-1R expression by prolonging the half-life of IGF-1R mRNA and promoting IGF-1-induced VSMC proliferation in murine atherosclerosis [95].