The laboratory tests on day 7 showed renal failure and severe liver damage, with creatinine levels of 1005 μmol/L, blood urea nitrogen levels of 35 mmol/L, total bilirubin levels of 83.8 μmol/L, alanine aminotransferase of 5910 IU/L, aspartate amino transferase of 7570 IU/L and prothrombin levels of 74% (Table 1). Here, F2 is linked to Renal insufficiency.