Further study by analyzing Pan-Cancer miRNA-mRNA interaction maps from the Cancer Genome Atlas (TCGA) matched miRNA-Seq and RNA-Seq data using StarBase V2.0 [32, 33] (http://starbase.sysu.edu.cn/index.php), we found that the inverse correlation between miR-141 and KLF12 is not only observed in ovarian cancers but also other cancer types (11/14) (Additional file 1: Figure S3). This evidence concerns the gene KLF12 and cancer.