The BRD1 promoter SNP, rs138880, was recently identified as the variant showing the most significant association with schizophrenia in a large GWAS meta-analysis (>11,000 cases and >10,000 controls) ensued by a family-based replication study (>6,000 individuals including >3,000 cases) [7]. The gene discussed is BRD1; the disease is schizophrenia.