DRD3 and schizophrenia: Although DRD3 was decreased by 26.76% and DRD3nf was decreased by 23.20% in substantia nigra of people with schizophrenia compared with controls, neither decrease reached statistical significance (F=1.471, df=53, P=0.231 and F=0.949, df=55, P=0.334, respectively; Figures 2d and e, respectively).