As previous studies reported, there were some other SNPs of HLA-DPB1 significantly associated with autoimmune diseases such as rheumatoid arthritis, Wegener’s granulomatosis, systemic sclerosis and infectious diseases like chronic hepatitis B infection18, 19, 20, 21, 26, 27. This evidence concerns the gene HLA-DPB1 and granulomatosis with polyangiitis.