The genetic deletion of Fgfr1–3, αKlotho, or Fgfr1–4 from the parathyroid glands by mating with PTH-Cre mice did not affect the plasma levels of calcium, phosphate, FGF23, and 1,25(OH)2D in the non-CKD and CKD groups. The gene discussed is FGF23; the disease is chronic kidney disease.