In contrast, concentrations of INF-gamma (144.31 ± 11.24 pg/ml, 250.18 ± 40.88 pg/mL) in plasma and BALF of mice in the TLR2-deficient mice group with asthma were significantly higher than that of wild-type group (P = 0.016, 0.010), data was presented in Figs 3 and 4. The gene discussed is TLR2; the disease is asthma.