After treated with recombinant mouse B7-H3, TLR2-deficient mice exhibited more severe airway inflammation, mucus cell metaplasia, and higher percentage of eosinophils and lymphocytes compared with the TLR2-deficient mice group with asthma, as shown in Table 1 and Figs 1 and 2. The gene discussed is TLR2; the disease is asthma.