Correspondingly, the levels of S380/T382/T383-phospho-PTEN (p-PTEN) and CK2 via its β-subunit of CSNK2B (CK2β) were elevated in GXP GBMs, and in the murine K-ras/p53 mutant GL26126, human p53/PTEN mutant T98G27 and human PTEN-null U87MG27 GBM cell lines as compared with control NS and WT adult brain (Fig. 2d and Supplementary Fig. 2d). This evidence concerns the gene TP53 and glioblastoma.