We found an increase in p62 protein following β-catenin knockdown and β-catenin-mediated repression of the SQSTM1 transcript, as well as increased autophagosome numbers (Figure 7), highlighting p62 regulation as a WNT/β-catenin-mediated mitophagy regulation mechanism in PTENWT melanoma cells (Figure 8). This evidence concerns the gene SQSTM1 and melanoma.