PTH and chronic kidney disease: On the other hand, the Kidney Disease: Improving Global Outcomes (KDIGO) Chronic Kidney Disease – Mineral and Bone Disorder (CKD-MBD) guidelines issued in 2009 [3] were less stringent with respect to PTH target levels than the previously used National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF-KDOQITM) guidelines [4].