As our study is an open study, we did various things when patients started to have dyskinesia such as frequent dosing of levodopa, lower amount of levodopa at each dose, reducing or discontinuing concomitant anti-Parkinson drugs such as a monoamine oxidase B inhibitor, entacapone, dopamine agonists, zonisamide, or istradefylline. The gene discussed is MAOB; the disease is drug-induced dyskinesia.