In this study, we have investigated the autoantibody levels against MDA-OxLDL in diabetic retinopathy, an observational analysis using a cross-sectional study design, and found that the levels of IgA type autoantibodies were increased in PDR patients as compared with DME or noDR and the type 2 patients in PDR group had the highest levels. This evidence concerns the gene CD79A and diabetic retinopathy.