TXN and acute lymphoblastic leukemia: HPB-ALL cells incubated with 150 nM TrxR plus 5 μM Trx1 overnight resulted in a significantly reduced binding of Tregalizumab from 661±91 to 147±45 mean fluorescence intensity (MFI) units of the BT-061 allophycocyanin (APC) staining (P=0.0041).