SKP2 and lung carcinoma: Among eight lung cancer cell lines and one immortalized line (BEAS-2B) tested, there is a general tendency of inversed protein levels between β-TrCP1 and FBXW2, as well as between FBXW2 and SKP2 (Fig. 6a), whereas the mRNA levels among them are similar in all lines (Supplementary Fig. 6a).