In contrast, in Cftr−/−mice, both types of ILC2 steadily increased throughout the infection (Fig. 1b) along with the expression of the ILC2 transcription factors, Rora, and Gata3 (Fig. 1d) and the production of ILC2 effector cytokines, IL-5 and IL-13 (Fig. 1e). This evidence concerns the gene RORA and infection.