TBK1 and frontotemporal dementia: Several other studies, looking at MND, frontotemporal dementia (FTD) and MND-FTD cases from both European and Asian populations, have also reported variants in TBK1, mostly loss-of-function (Borghero et al., 2016, Gijselinck et al., 2015, Le Ber et al., 2015, Pottier et al., 2015, Shu et al., 2016, Tsai et al., 2016, van Rheenen et al., 2016, Williams et al., 2015).