NEK1 and mild neurocognitive disorder: Loss-of-function variants in NEK1 have been associated with MND in two recent studies of both familial and sporadic MND cases (Brenner et al., 2016, Kenna et al., 2016), following an earlier study of mostly sporadic cases that highlighted NEK1 as a candidate gene (Cirulli et al., 2015, Exome Aggregation Consortium (ExAC)).