TIMP1 and neoplasm: In 4T1 tumor section specimens, we found that 150 mg/kg decreased MMP-9 to 38.54% compared with 75% in the control group, increased TIMP-1 to 76.04% compared with 31.25% in the control group, and increased TIMP-2 to 66.15% compared with 33.33% in the control group, respectively.