By examining the protein levels of Cp, LCN2 and Postn in the lung tissues from wild-type (WT) and Gprc5a-ko mice via immunohistochemical (IHC) staining assay, we found that Cp, LCN2, and Postn protein levels were all significantly increased in tumor-containing tissues (T) from Gprc5a-ko mouse lungs, compared to wild type ones (N) (Figure 3). The gene discussed is LCN2; the disease is neoplasm.