Potent αDC1s, induced by cytokine cocktails containing IL-1β, TNF-α, INF-α, IFN-γ, and poly I:C, generate strong functional cytotoxic T lymphocytes (CTLs) in several type of cancers and are, on average, 20-fold more active than conventional DCs [14, 15]. Here, IL1B is linked to cancer.