Another study on oral squamous cell carcinoma (OSCC) reported that the Ki-67 proliferation index at the time of diagnosis had no significant correlation with the response to radiation therapy; in contrast, the reduction in the growth fraction (decrease in proliferation index) after radiation therapy at a total dose of 10 Gy was significantly correlated with the CR rate [19]. This evidence concerns the gene MKI67 and oral cavity squamous cell carcinoma.