MBL2 and pneumococcal meningitis: In a prospective genetic association study, including 299 patients with pneumococcal meningitis and 216 controls, we previously showed that the risk for contracting pneumococcal meningitis was substantially increased for white individuals homozygous with the defective MBL2 0/0 genotype (odds ratio 8.21, 95% confidence interval 1.05–64.1; P = 0.017) [30].