However, at the protein level, xCT expression was significantly upregulated in NAWM of MS patients compared to controls, as measured using semi-quantitative Western blotting (relative expression controls vs. MS patients: 100.00 ± 11.51 vs. 229.30 ± 44.81%; p = 0.045, Fig. 1b). Here, SLC7A11 is linked to myeloid sarcoma.