TCF4 and colorectal carcinoma: In 64 CRC tissue samples, we were able to establish inverse correlation between the expression levels of miR-181a-5p and β-catenin (r = −0.562, P < 0.001), and between those of miR-181a-5p and TCF4 (r = −0.518, P < 0.001) (Fig. 5e).