We found that in the ApcMin/+ small and large intestine, Dll4 is strongly expressed in the tumor epithelium, including in the goblet and Paneth cell lineages (Figs. 1c, 2c, and Additional file 4: Figure S1A-B), and it is also present in the tumor endothelium (Additional file 4: Figure S1C-D). This evidence concerns the gene DLL4 and neoplasm.