MTHFR and coronary artery disorder: As shown in Tables 2 and 3, the univariate model indicated that the 5 SNPs (1) rs1800595 (FVR), (2) rs1801133 (MTHFR), (3) rs5918 (HPA-1), (4) rs1799752 (ACE), and (5) rs7412 and rs429358 (ApoE) were significantly associated with CAD disease under different genetic association models.