HPSE and coronary artery disorder: More specifically, it has been found that five variants; rs1800595 (FVR), rs1801133 (MTHFR), rs5918 (HPA-1), rs1799752 (ACE), and rs7412 and rs429358 (ApoE) were significantly associated with CAD susceptibility under different genetic models in the current sample of Egyptian CAD patients.