Indeed, Cappell et al. reported that FSIP1 depletion can enhance paclitaxel-induced mitotic arrest and/or the formation of micronucleated cells in NSCLC cell lines, and FSIP1-mediated alterations in microtubule and dynein function may support the microtubule network and enhance mitotic robustness in cancer cells [3]. The gene discussed is FSIP1; the disease is non-small cell lung carcinoma.