In contrast, addition of HA to the epithelial and noninvasive cancer cell line MCF7 and the mammary fibrocystic cell line MCF10A had rather opposite effects leading to further reduction of the already low levels of ZEB1, likely owing to the fact that one important receptor of HA, CD44s, is not expressed in MCF7 and MCF10A (Figure 1A) [19]. Here, ZEB1 is linked to cancer.