IRF7 and systemic lupus erythematosus: For example, MX1, LY6E, IFIT1, PLSCR1 and IRF7 were up-regulated in Caucasian SLE patients [34–36]; MX1, LY6E, and IFIT1, as well as OAS1 and OAS3, were up-regulated in Chinese SLE patients [37–40]; and IFITM1 was up-regulated in the platelets of Caucasian SLE patients [41].