TGFB1 and colorectal cancer: As TGF‐beta is a classical immune suppressor as well as a key modulator of cellular crosstalk, the discovery that high levels of TGF‐beta correlate with poor prognosis may imply that colorectal cancer exploits this cytokine in tumoral immune evasion, besides affecting CAF‐mediated secretion of pro‐tumorigenic factors (Tauriello and Batlle, 2016).