However, numerous clinical studies support the notion that EMT gene signatures predict poor prognosis based on correlation between the expressions of mesenchymal markers such as vimentin, N‐cadherin, fibronectin, and tumor aggressiveness and poor clinical outcome in various cancer tissues by immunohistochemistry or tissue array (Aleskandarany et al., 2014; Liu et al., 2013; Nitta et al., 2014; Sarrió et al., 2008; Tsang et al., 2013). The gene discussed is VIM; the disease is cancer.