Regarding the CCl4 model that mimics a compensated cirrhosis, no mortality events were reported with the different treatments and only animals treated with atorvastatin showed a higher weight loss (10 g vs 3 g in vehicle) and a 7.69% hepatic or muscular toxicity (ALT > 500 IU/L and CK > 6000 IU/L, respectively) (Table 2, Suppl. The gene discussed is GPT; the disease is Cirrhosis.