MCAM and atherosclerosis: Because CD146 contributes to oxLDL uptake and retention of macrophage foam cells, and targeting macrophagic CD146 with the AA98 antibody (which recognizes murine CD146, Supplementary information, Figure S13) inhibited lipid uptake and promoted emigration of macrophages, macrophagic CD146 may serve as a potential therapeutic target for atherosclerosis.