Given the MG132-sensitive nature of SopA-mediated TRIM56 ubiquitination and its preference for the synthesis of mostly degradative K48- and K11-chain types, we monitored the abundance of TRIM56 and TRIM65 proteins after infection of cells with S. Typhimurium WT, sopA-deficient or sopA-complemented strains. The gene discussed is TRIM65; the disease is infection.