WNT5A and tuberculosis: We showed that Wnt5a and its putative receptor Frizzled5 (Fzd5) are present in lung biopsies of TB-patients, that mycobacteria induce Wnt5a in macrophages in a TLR-NF-kappaB dependent manner, and that Wnt5a exerts a distinct immunomodulatory function on immune cells (52).