We compared the association of non-MHC genetic regions contributing to pathways in the RA data (S8 Fig) and found generally weaker association than in T1D, except in PTPN22, where the RA association was equally strong and in IL2RA (rs10795791 and rs2104286) and IL2RB regions (rs3218253 and rs743777), where there were stronger associations. The gene discussed is PTPN22; the disease is rheumatoid arthritis.