PPARG and metabolic syndrome: These may also suggest that the purpose of fruit and vegetable rich diet in metabolic syndrome does not only mean high fiber diet to reduce caloric intake, but to gain antioxidative and anti-lipotoxic effects to prevent further progression and complications, even though dietary supplement of short-chain fatty acid, the main products of dietary fiber fermentation, obviously prevents and reverses HFD-induced metabolic abnormalities by decreasing PPARγ expression and activity [53].