PPARγ, activated as PPARγ-retinoid x receptor functional heterodimer, contributes to FFAs uptake and hepatic steatosis through PPARγ-responsive genes, such as lipoprotein lipase (LPL), fatty acid translocase, fatty acid transport proteins and adipocyte protein 2 (aP2) [11–14]. The gene discussed is PPARG; the disease is Hepatic steatosis.