In normal murine fibroblasts, normal hippocampal neurons, melanoma cells, a variety of human tumor cell lines, gliobastoma, non-small cell lung cancer, breast carcinoma, skin cancer as well as head and neck cancer, EGR1 is either pro-apoptotic or suppresses growth [27–29, 33, 34, 47, 48, 50–53]. The gene discussed is EGR1; the disease is skin neoplasm.