Shi et al. identified KIF20A is a downstream target gene of Glioma-associated oncogene 2 (Gli2) via the Forkhead Box M1 (FoxM1)-MMB complex, and reported the Gli2-KIF20A axis plays an essential role in the growth and progression of hepatocellular carcinoma and KIF20A could serve as an important prognostic biomarker [27]. The gene discussed is GLI2; the disease is hepatocellular carcinoma.